A group of top national leaders in public health will gather for a panel discussion moderated by Sandro Galea, MD, DrPH. The panelists will discuss the erosion of public health infrastructure funding and its consequences for preparedness, workforce stability, and the health of the population. The panelists will situate these challenges in a broader political and economic context, including the reality of shrinking federal, state, and local budgets. The conversation also will focus on strategies to safeguard core public health functions and identify opportunities to reimagine sustainable investment in population health.